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HOE-S 785026 trihydrochloride is a blue fluorescent DNA nuclear stain supplied as a solid. It binds to the minor groove of double-stranded DNA and is used for nuclear staining in fluorescence microscopy and cell-based assays. Available in multiple pack sizes and high purity for research applications.
Blue fluorescent dye suitable for DNA/nuclear staining.
Binds the minor groove of double-stranded DNA for reliable nuclear labeling.
High purity for reproducible experimental results.
Available in small quantities to support assay development and optimization.
Compatible with fluorescence microscopy and cell-based assays.
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VO-Ohpic trihydrate is a vanadium-containing small-molecule inhibitor of PTEN used in biochemical and cell-based research to probe PI3K/AKT signaling. It reversibly inhibits PTEN with low-nanomolar potency and is supplied as the trihydrate form to aid stability and handling.
Potent PTEN inhibition (IC50 ≈ 46 ± 10 nM).
Vanadium-containing complex for targeted phosphatase interaction.
Suitable for biochemical and cell-based assays probing PI3K/AKT signaling.
Trihydrate form to improve compound stability during storage and handling.
Available in small, research-grade quantities for laboratory use.
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RNase L-IN-1 trihydrochloride is the trihydrochloride salt form of a small-molecule inhibitor of RNase L, supplied for research use to study RNase L-mediated RNA degradation, antiviral responses, and inflammation. The compound is provided as a solid salt suitable for biochemical and cellular assays.
Inhibits RNase L activity for mechanistic and antiviral research.
Trihydrochloride salt form improves solubility and handling.
High purity (~98.1%) suitable for research applications.
Yellow to brown solid appearance, powder form for storage.
Molecular formula C27H35FN6O3S; molecular weight 542.67 g/mol.
Store powder at -20°C for long-term stability; follow supplier guidelines.
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VO-Ohpic trihydrate (CAS 476310-60-8) is a highly selective small-molecule inhibitor of the lipid phosphatase PTEN (phosphatase and tensin homolog) with an in vitro IC50 of 35 nM VO-Ohpic shows marked selectivity for PTEN over other phosphatases including CBPs SopB myotubularin SAC1 and PTP- In cell-based assays VO-Ohpic induces dose-dependent phosphorylation of Akt at Ser473 and Thr308 saturating at 75 nM and promotes Akt functional activation as indicated by decreased FoxO3a transcriptional activity In vivo VO-Ohpic administration in MDA PCa-2b tumor xenograft mice results in reduced tumor growth and increased survival This compound serves as a valuable tool for investigating PTEN function and its modulation in insulin signaling glucose uptake and cancer research
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Peramivir Trihydrate (CAS 1041434-82-5) is a small-molecule inhibitor targeting influenza viral neuraminidase It is designed to inhibit neuraminidase activity thereby impeding viral particle release and the spread of infection Peramivir Trihydrate exerts its biological activity primarily through competitive inhibition of neuraminidase as a transition-state analog In experimental studies Peramivir Trihydrate demonstrates neuraminidase inhibitory activity with an IC50 of approximately 0 09 nM Based on these pharmacological properties Peramivir Trihydrate holds research potential in investigating influenza virus replication antiviral efficacy and neuraminidase-mediated viral dissemination
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Alendronate sodium trihydrate (G-704650 MK-217) a nitrogen-containing bisphosphonate is a potent inhibitor of bone resorption used for the treatment and prevention of osteoporosis
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Irinotecan HCl Trihydrate is a hydrochloride trihydrate of irinotecan (Camptosar Campto CPT-11) which is a topoisomerase I inhibitor with IC50 of 15 8 and 5 17 M for LoVo cells and HT-29 cells respectively
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Peramivir Trihydrate (BCX-1812 RWJ-270201 S-021812) is a trihydrate of the anti-infection agent peramivir which is a transition-state analogue and a potent specific influenza viral neuraminidase inhibitor with an IC50 of median 0 09 nM
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